Publikationen

    Risk Factors for Preterm Birth following Open Fetal Myelomeningocele Repair: Results from a Prospective Cohort

    Maike Katja Kahr 1 2, Franziska Winder 3 4, Ladina Vonzun 3 4, Martin Meuli 5 4, Luca Mazzone 5 4, Ueli Moehrlen 5 4, Franziska Krähenmann 3 4, Margaret Hüsler 3 4, Roland Zimmermann 3 4, Nicole Ochsenbein-Kölble 3 4

    etal myelomeningocele (fMMC) repair is a therapeutic option in selected cases. This study aimed to identify risk factors for preterm birth (PTB) following open fMMC repair.

    PMID: 31104051 DOI: 10.1159/000500048

    Journal: Karger Fetal Diagnosis and Therapie - published online: May 17, 2019

    DateEnglish: 01/01/2020

    1Division of Obstetrics, University Hospital of Zürich, Zurich, Switzerland, maikekatja.kahr@usz.ch.

    2Zurich Center for Fetal Diagnosis and Therapy, University of Zurich, Zurich, Switzerland, maikekatja.kahr@usz.ch.

    3Division of Obstetrics, University Hospital of Zürich, Zurich, Switzerland.

    4Zurich Center for Fetal Diagnosis and Therapy, University of Zurich, Zurich, Switzerland.

    5Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland.

    Inclusion Cysts after Fetal Spina Bifida Repair: A Third Hit?

    Pascal Heye 1 2, Ueli Moehrlen 3 4 5 6, Luca Mazzone 3 4 5 6, Robert Weil 3 4 7, Stefan Altermatt 3 4 7, David-Alexander Wille 4 8, Ianina Scheer 4 9, Martin Meuli 3 4 5 6, Maya Horst 3 4 10

    Fetal spina bifida repair (fSBR) has proven effective in the reversibility of hindbrain herniation, lower rate of shunt-dependent hydrocephalus, and independent ambulation. Besides distinct advantages, there are also concerns related to fSBR. One of these is the postnatal occurrence of inclusion cysts (IC).

    PMID: 30199879 DOI: 10.1159/000491877

    Journal: Karger Fetal Diagnosis and Therapie - published online September 10, 2018

    DateEnglish: 01/07/2019

    1Department of Pediatric Surgery, University Children's Hospital Zurich, Zürich, Switzerland, pascalheye@gmail.com.

    2Children's Research Center, University Children's Hospital Zurich, Zürich, Switzerland, pascalheye@gmail.com.

    3Department of Pediatric Surgery, University Children's Hospital Zurich, Zürich, Switzerland.

    4Children's Research Center, University Children's Hospital Zurich, Zürich, Switzerland.

    5Division of Fetal Surgery, University Children's Hospital Zurich, Zürich, Switzerland.

    6The Zurich Center for Fetal Diagnosis and Therapy, University of Zurich, Zürich, Switzerland.

    7Division of Pediatric Neurosurgery, University Children's Hospital Zurich, Zürich, Switzerland.

    8Division of Pediatric Neurology, University Children's Hospital Zurich, Zürich, Switzerland.

    9Division of Diagnostic Imaging, University Children's Hospital Zurich, Zürich, Switzerland.

    10Division of Pediatric Urology, University Children's Hospital Zurich, Zürich, Switzerland.

    Open Spina Bifida: Why Not Fetal Surgery?

    Luca Mazzone 1, 2, 3, Ueli Moehrlen 4, 5, 6, Barbara Casanova 4, 5, 6, Samira Ryf 4, Nicole Ochsenbein-Kölble 7, 5, Roland Zimmermann 7, 5, Franziska Kraehenmann 7, 5, Martin Meuli 4, 5, 6

    The majority of patients counseled for prenatal open spina bifida repair (SBR) do not undergo fetal surgery. The aim of this study was to analyze the reasons for this phenomenon

    PMID: 30205373 DOI: 10.1159/000491751

    Journal: Karger Fetal Diagnosis and Therapie - published online: September 11, 2018

    DateEnglish: 01/06/2019

    1 Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland, luca.mazzone@kispi.uzh.ch.

    2 The Zurich Center for Fetal Diagnosis and Therapy, Zurich, Switzerland, luca.mazzone@kispi.uzh.ch.

    3 Children's Research Center (CRC), Zurich, Switzerland, luca.mazzone@kispi.uzh.ch.

    4 Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland.

    5 The Zurich Center for Fetal Diagnosis and Therapy, Zurich, Switzerland.

    6 Children's Research Center (CRC), Zurich, Switzerland.

    7 Department of Obstetrics, University Hospital Zurich, Zurich, Switzerland.

    In utero Plastic Surgery in Zurich: Successful Use of Distally Pedicled Random Pattern Transposition Flaps for Definitive Skin Closure during Open Fetal Spina Bifida Repair

    Martin Meuli  1 , Claudia Meuli-Simmen, Luca Mazzone, Sasha J Tharakan, Roland Zimmermann, Nicole Ochsenbein, Ueli Moehrlen

    One of the intraoperative challenges of fetal spina bifida repair is skin closure when there is an extended skin defect. Thus, we examined whether distally pedicled random pattern transposition flaps (TFs) are a valid option to overcome this problem.

    PMID: 29258087 DOI: 10.1159/000479926

    Journal: Karger Fetal Diagnosis and Therapie - published online: December 20, 2017

    DateEnglish: 01/10/2018

    1 Zurich Center for Fetal Diagnosis and Therapy, University Children's Hospital Zurich, Zurich, Switzerland.

    Maternal Complications following Open Fetal Myelomeningocele Repair at the Zurich Center for Fetal Diagnosis and Therapy

    Franziska M Winder 1, Ladina Vonzun 2, Martin Meuli 3, Ueli Moehrlen 3, Luca Mazzone 3, Franziska Krähenmann 4, Margret Hüsler 4, Roland Zimmermann 4, Nicole Ochsenbein-Kölble 4

    Despite undoubtable benefits of open fetal myelomeningocele (fMMC) repair, there are considerable maternal risks. The aim of this study was to evaluate and systematically categorize maternal complications after open fMMC repair.

    PMID: 30428477 DOI: 10.1159/000494024

    Journal: Karger Fetal Diagnosis and Therapie - published online: November 14, 2018

    DateEnglish: 01/09/2018

    1Department of Obstetrics, University Hospital Zurich, Zurich, Switzerland, Franziska.Winder@usz.ch.

    2Department of Obstetrics, University Hospital Zurich, Zurich, Switzerland.

    3Department of Pediatric Surgery, Zurich Center for Fetal Diagnosis and Therapy, University Children's Hospital Zurich, Zurich, Switzerland.

    4Department of Obstetrics, Zurich Center for Fetal Diagnosis and Therapy, University Hospital Zurich, Zurich, Switzerland.